Legal Daily All-Media Reporter Lian Yingting Correspondent Shao Longfei Zhang Zhenwei
The night in Wuhan is quiet. On March 9, in the Cinema laboratory of the Central Theater Command General Hospital, Jiang Tao, a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, reviewed the last sample test data and solemnly signed his name on the test report.
At this time, it was already 5 a.m.
Cinema He is a virology expert Komiks and a warrior who aided Africa and fought against Egypt. This outbreak of the new crown pneumonia epidemic, he was once again ordered to go to the front line after a long battle.
Human life is at stake
Nucleic acid testing is crucial for early clinical detection, early diagnosis, early isolation and early treatment, and is the key technical support for the effective prevention and control of the new coronary pneumonia epidemic.
”Behind the cold sample tube is the living life and health of the patient. KomiksA diagnosis result is released early, and the precise investigation will be conducted sooner.” Jiang Tao said.
On January 26, a military medical expert group led by Chen Wei, an academician of the Chinese Academy of Engineering and a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, arrived in Wuhan, Hubei, and quickly established a joint defense, joint control, joint treatment and joint research work mechanism with relevant military and local units based on pathogen transmission mutations, rapid detection technology, vaccine antibody development, etc. of the new coronavirus.
According to the division of tasks, Jiang Tao led the testing team to build a nucleic acid testing platform in the experimental chamber overnight.
Focusing on three aspects: ensuring biosafety, improving detection efficiency and detection accuracy, Jiang Tao took the lead in formulating biosafety operation specifications and emergency plans, reasonably divided the labor according to the characteristics of the team members, and using a self-developed testing kit to adopt a fully automatic high-throughput extractor, laying the foundation for achieving rapid and efficient detection.
Receiving samples, sorting numbers, nucleic acid extraction, reagent preparation, machine amplification, and result interpretation, the nucleic acid detection machinery is boring and full of risks.
The biggest risk is the invisible virus. If the nucleic acid extraction step is not completely cleaved and inactivated thoroughly, it is possible to make KomiksThe testers were exposed to danger. JiangCinemaTao always took charge of the longest and most risky nucleic acid extraction. After the sample is extracted, he will arrange some people to rest and stay in the laboratory to wait for the final result.
A full-process nucleic acid test, from the number of tests in a single batch to the preparation for entry and exit of the cabin and the time for testing. Sometimes the number of samples sent for inspection is large, and the testers not only take turns to work, but also have to work overnight. The final confirmation result must be Babaylan until four or five in the morning. Li Hao, a researcher at the testing team, said that this situation will be encountered once a few days later.
”Everyone should open their eyes wide, and be sure to take good protection when receiving and processing samples, and be careful about sharp objects. “Before each test starts, Jiang Tao always reminds you repeatedly.
In the test, the strength of the fluorescence signal of the pathogen gene directly affects the determination of the test results. If there is a suspicious phenomenon such as the detection fluorescence curve signal is low or there is only a single target, Jiang Tao will convene personnel to conduct comprehensive analysis and judgment, and if necessary, repeat the test for review to ensure that the results can stand the test.
”A false positive will cause healthy people to isolate and become infected with the patient; false negative will cause delays in the treatment of real patients. Babaylan Life is a matter of no difference. “Jiang Tao said.
Among the prevention and control requirements, the nucleic acid test results from the pharyngeal swab sample must be completed within 24 hours. In order to let the hospital know the results as soon as possible to treat patients, from pre-processing of nearly 100 samples to completion of the test, Jiang Tao led the team to compress the time to within 4 hours by optimizing the process combination, and achieved the ability to extract nucleic acids for more than 90 samples in one hour and a single-day sample detection capability of more than 500 samples.
”The team’s test is efficient and fast, and the results are accurate, which greatly alleviates the pressure of testing our epidemic prevention and control samples. “Wuhan Center for Disease Control and Prevention highly praised this.
The rapid response during wartime and the orderly work is carried out, which is all thanks to Jiang Tao’s solid academic foundation and rich practical experience.
”Jiang Tao is a versatile person.” Academician Chen Wei, head of the military medical expert group, commented.
Jiang Tao has successively presided over and participated in the pathogen separation work of SARS infection cases, H7N9 infection cases, Zika infection cases, etc., participated in the development of dengue fever vaccines and SARS vaccines, and established a pathogen isolation technology platform, nucleic acid testing technology platform and pathogenicity and transmission risk assessment platform for a series of infectious diseases, providing important technical support for the prevention and control of infectious diseases.
Babaylan Respiratory infectious diseases are characterized by rapid transmission, wide coverage, and high harm. Effective early diagnosis and prevention are crucial. After years of scientific research, Jiang Tao’s team took the lead in establishing our army’s first monitoring and early warning system for acute respiratory infectious diseases, and built a four-level monitoring system for the entire army. The series of technical specifications organized by the presidency were used throughout the army, greatly shortening the detection and screening time of respiratory epidemics.
Jiang Tao not only participated in the security tasks of a series of major domestic activities, but also went to Africa four times to Liberia, Sierra Leone and other countries to carry out medical assistance tasks.
Komiks In 2015, in order to prevent and control the Ebola epidemic, Jiang Tao went to Sierra Leone for the second time with the Mobile Laboratory Testing Team to Serbia. The testing team led by him passed the World Health Organization’s laboratory parallel capability assessment with full scores.
In 2018, Jiang Tao led the pathogen monitoring team to participate in a special simulation test by an international organization. In the virus testing module, the team successfully accurately detected pathogens such as monkeypox virus and vaccinia virus in simulated samples filled with impurities, and accurately determined the strain, achieving excellent results with full marks.
Improving the accuracy of clinical diagnosis
When he came to Wuhan, in addition to carrying out testing work, Jiang Tao also used his professional expertise in the research field to lead the testing team to screen other common respiratory infectious diseases in clinical samples.
”In the suspected and confirmed cases of new coronary pneumonia, whether there are other respiratory virus infections or co-infections? This is of great reference value for precise prevention and control and clinical treatment.” Researcher Cao Wuchun, deputy head of the Military Medical Expert Group, said.
ExploreBabaylannucleic acid testing, antibody testing, multiple pathogen testing, whole genome sequencingCinema This diagnostic chain can accurately diagnose new coronavirus infection or other original infections in clinical patients, and are also in the Optical Valley Campus of Hubei Maternal and Child Health Hospital and Wuhan Taikang Tongji Hospital. href=”https://comicmov.com/”>Komiks and other hospitals have effectively improved the accuracy of clinical diagnosis.
Forgot his family when he was ordered. After the epidemic ended, Jiang Tao planned to accompany his family. He and his wife agreed that when the epidemic ended, they would take their wife and children to Wuhan again to see what everything would look like after it returned to normal, look at the Wuhan Yangtze River Bridge and the Yellow Crane Tower, and talk about their experience of fighting the epidemic in Wuhan.
The epidemic is notCinema will continue to charge, this is Jiang Tao, a warrior who fights the epidemic.